Department of Chemistry
PO Box 210172
Cincinnati, OH 45221-0172

513.556.9273

suri.iyer@uc.edu

 

Dr. Suri S. Iyer

Curriculum Vitae

Carbohydrates for Biosensors

 

Suri S. Iyer is an Assistant Professor of Chemistry in the Sensor division. He has broad research interests in carbohydrate chemistry and the application of stable carbohydrate ligands to biosensor platforms. His doctoral work under the direction of Prof. Malcolm Chisholm encompassed the synthesis and application of C-3 symmetric chiral single site metal alkoxides for the polymerization of lactides and lactones. He then moved to the Emory School of Medicine, Atlanta, GA where he worked under the tutelage of Professor Elliot Chaikof to develop heparin sulfate and hyaluronan mimetics. Heparin sulfate and hyaluronan are important carbohydrates that are involved in several biological processes such as anticoagulation, osteoporosis, and osteoarthritis and have significant potential applications as wound-healing agents and antiviral drugs. He continued his work in carbohydrate chemistry in the Biosensor Group at the Los Alamos National Laboratory, NM. Suri was involved in the application of the Los Alamos Biosensor platform, a membrane based detection platform that allows proximity induced fluorescence resonance transfer in response to multivalent binding events, to detect and differentiate between various types of Influenza virus.

 

Research Areas

My research interests can be summed up in 3 words, "Carbohydrates for biosensors". Currently, my group and I are establishing an independent research program in the area of pathogen detection using oligosaccharides and contributing to ongoing sensor research in the department.   Since most harmful bacteria and viruses recognize and bind to cell surface carbohydrates in a multivalent manner prior to cell infection, our work emphasizes the first step of the infection process, i.e., the recognition of the cell surface carbohydrates by the pathogens. However, unlike proteins and DNA, Nature's third class of biopolymers, carbohydrate recognition motifs are not well understood as they are multifaceted and extremely complex.  We have extensive experience in developing versatile synthetic strategies for complex carbohydrates and we are  interested in developing ligands for detection of harmful pathogens since the development of high affinity, sensitive, selective and robust ligands as integral components of biosensors is crucial for emerging detection technologies

 

Hobbies

  • Organic Chemistry
  • Comics (Calvin & Hobbes, Charlie Brown)
  • Running

 

Iyer group members

 

 

From left to right: Sujit Mahajan, Shalyajit Jadhav, Dr. Ramesh Kale, Duane Hatch, Dr. Suri S. Iyer, Kenry Korman, David Siler and Stephany Jones.

 

 

 

 

   

 

 


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Chemical Sensors and Bisensors Group
404 Crosley
University of Cincinnati
PO Box 210172
Cincinnati, Ohio 45221-0172

Phone: 513.556.9200
Fax: 513.556.9239
 

Copyright Information 2006